Van Helsing could of been a really great story but the plot was kind of loose. There was nothing really driving us to care about the characters, especially the main character. I almost didn't care that they had to kill Dracula, either. Some things were too obvious, and other things were too obscure and it didn't really lead you along very well, so I felt like I was just drifting through the film in a very unattatched way. The effects were very cool for the most part - I especially enjoyed the werewolves (I'm a werewolf fan and picky and thought they did a neat job). The acting was okay - some people needed to choose an accent and KEEP it. And those female vampire sidekicks were just weird. They reminded me of the Furies from Xena or something - their clawed hands and movements were the same for every emotion.
All in all I totally didn't care about the film and having watched it, leaves me with nothing. *shrugs* I've definetly seen more entertaining films.